Vasculitis & polymyalgia rheumatica
Neutrophilic dermatosis and hidradenitis suppurativa in patients with Behçet's disease: A neutrophilic disease in the spectrum of autoinflammatory syndromes
Authors' conclusion
PG seems overrepresented in patients with BD. Biotherapies such as anti-TNFα, ustekinumab and tocilizumab appear to be promising to treat refractory ND or HS associated with BD.
Study context
- Population
- Patients with Behçet's disease (BD) and associated neutrophilic dermatosis (ND) or hidradenitis suppurativa (HS), identified among 1462 patients with BDamong 1462 BD patients
- Participants
- 20 patients
- Outcome
- ND or HS associated with BD
Main finding
As reported in the abstract
- Patients with ND or HS associated with BD
- 20 (1.4%)
- HS
- 13
- Pyoderma gangrenosum (PG)
- 6
- SAPHO
- 1
- PG prevalence in BD
- 400/100 000
- HS at Hurley 1 stage
- 69%
- Complete or partial responses in refractory ND or HS with anti-TNFα
- 9 cases
- Complete or partial responses with ustekinumab
- 3 cases
- Complete or partial responses with tocilizumab
- 1 case
Observational data: associations, not effects.
Further findings
BD involvement
- Bipolar aphthosis
- 13
- Vascular
- 6
- Neurologic
- 5
- Ocular
- 4
Treatment received
- Colchicine
- 20
- GC
- 12
- Anti-TNFα
- 9
Original publication
Neutrophilic dermatosis and hidradenitis suppurativa in patients with Behçet's disease: A neutrophilic disease in the spectrum of autoinflammatory syndromes. Semin Arthritis Rheum. Published 13 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →