Lupus & antiphospholipid syndrome
Navigating the gap: the challenge of applying treat-to-target in routine lupus care—a national perspective
Authors' conclusion
This CA highlights significant challenges in implementing evidence-based SLE management in Spain, particularly regarding the adoption of the T2T strategy.
Study context
- Population
- Rheumatologists managing systemic lupus erythematosus (SLE) in Spain
- Outcome
- Practice patterns, barriers and facilitators in SLE management and T2T adoption
Methodological detailscontextual analysis framework (Basel Approach for coNtextual ANAlysis), literature review, structured focus groups
- Contextual analysis framework (Basel Approach for coNtextual ANAlysis)
- Literature review
- Structured focus groups
Main finding
As reported in the abstract
- Considerable variability in SLE management across regions and healthcare centres
- Major barriers: disease complexity, delayed diagnosis, workforce shortages, limited training and awareness among healthcare professionals, insufficient multidisciplinary collaboration, underutilisation and lack of standardisation of clinical indices, inadequate patient education, poor integration of patient-reported outcomes into electronic medical records
- Implementing treat-to-target (T2T) and clinical guidelines rare due to perceived complexity, time constraints, lack of digital support and limited training
- Proposed strategies: improved training, structured referral pathways, digital solutions, shared decision-making tools, practical checklists, multidisciplinary care networks
Original publication
Navigating the gap: the challenge of applying treat-to-target in routine lupus care—a national perspective. Lupus Sci Med. Published 21 August 2026. doi:10.
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