Spondyloarthritis & psoriatic arthritis

Natural language processing to identify and characterize spondyloarthritis in clinical practice

RMD OpenPublished Retrospective cohort study

Authors' conclusion

The application of NLP technology facilitated the characterisation of the SpA patient profile, including demographics, clinical features, comorbidities and treatments.

Study context

Population
All patients with spondyloarthritis (SpA) (including psoriatic arthritis (PsA)) at Hospital Universitario La Paz, 2020–2022of 639,474 hospital patients
Participants
4,337 patients
Outcome
Clinical profile of SpA patients (demographics, SpA subtypes, comorbidities, treatments) extracted by NLP
Methodological detailsobservational, single-centre, natural language processing (NLP)-based extraction from unstructured electronic health records (EHRs)
  • Observational
  • Single-centre
  • NLP-based extraction from unstructured EHRs

Main finding

As reported in the abstract

SpA clinical profile
SpA diagnosis in hospital population
0.7%
Men
55.3%
Mean age (years)
50.9
Peripheral SpA (incl. PsA)
31.6%
Axial SpA
20.9%
Both axial and peripheral SpA
3.7%
SpA subtype not reported
43.7%
Hypertension
25.0%
Dyslipidaemia
22.2%
Diabetes mellitus
15.5%
MTX (most used csDMARD)
25.3%
Adalimumab (most used bDMARD)
10.6%

Observational data: associations, not effects.

Further findings

NLP performance in detecting SpA clinical entities (precision, recall, F-1 score)

All assessed F-1 score values over 0.80; high precision and recall

Original publication

Natural language processing to identify and characterize spondyloarthritis in clinical practice. RMD Open. Published 24 May 2024. doi:10.1136/rmdopen-2024-004302

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