Spondyloarthritis & psoriatic arthritis
Risk of cardiovascular disease decreases over time in psoriatic arthritis but not in spondylarthritis: meta-analysis of longitudinal studies
Authors' conclusion
The SLR and meta-analysis confirmed the increased incidence of CVD in both SpA and PsA patients compared with the general population, although the increase seems to be less prominent in PsA than in SpA.
Study context
- Population
- Longitudinal studies (study period ≥5 years) including SpA/PsA patients and general population24 articles meta-analysed (34 in systematic literature review (SLR))
- Comparison
- SpA and PsA vs general population
- Outcome
- Occurrence of CVD, including ischaemic heart disease, stroke and death from CV causes
Methodological detailsrandom-effects model, controlled observational studies, study period of at least 5 years
- Random-effects model
- Controlled observational studies
- Study period of at least 5 years
Pooled result
As reported in the abstract
Overall incidence of CVD
Each group vs general populationHazard ratio (95% CI)
PsA
1.28(1.15–1.43)
SpA
1.45(1.22–1.72)
Further pooled results
Trend in cardiovascular disease (CVD) incidence over time
- Incidence tended to decrease over time in PsA but not in SpA
Original publication
Risk of cardiovascular disease decreases over time in psoriatic arthritis but not in spondylarthritis: meta-analysis of longitudinal studies. Rheumatology (Oxford). Published 16 February 2024. doi:10.
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