Nailfold videocapillaroscopy abnormalities in autoimmune inflammatory myopathy subsets
Authors' conclusion
Dermatomyositis, scleromyositis and anti-synthetase syndrome showed frequent NVC abnormalities, although no NVC pattern was associated with a particular subset in our study.
Study context
- Population
- Autoimmune inflammatory myopathies (AIM) subjects from the Canadian Inflammatory Myopathy Study (CIMS), a prospective cohort; 71% female, median disease duration 1 year71% female
- Participants
- 99 subjects
- Exposure
- Nailfold videocapillaroscopy (NVC) features and patterns compared between AIM subsets
- Dermatomyositisn = 41
- Scleromyositisn = 24
- Anti-synthetase syndromen = 16
- Immune-mediated necrotizing myopathyn = 7
- Inclusion body myositisn = 8
- Polymyositisn = 3
- Outcome
- NVC abnormalities (capillary density, ectasias, giant and ramified capillaries, microhaemorrhages, NVC patterns) in AIM subsets
Methodological detailsprospective cohort (CIMS), clinico-sero-pathological approach
- Prospective cohort (CIMS)
- Clinico-sero-pathological approach
Main finding
As reported in the abstract
Decreased capillary density (most frequent NVC abnormality)
- NVC abnormalities absent in IMNM, IBM and PM
- 0
Observational data: associations, not effects.
Original publication
Nailfold videocapillaroscopy abnormalities in autoimmune inflammatory myopathy subsets. Rheumatology (Oxford). Published 5 November 2025. doi:10.
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