Inflammatory myopathies

Anifrolumab Therapy in Dermatomyositis: New Insights From Refractory Patients

J RheumatolPublished Case series

Authors' conclusion

The data we collected showed a significant reduction in CDASI-A values.

Study context

Population
Patients with dermatomyositis (DM) with cutaneous involvement refractory to different immunosuppressive treatments50% female, mean age 60 years
Participants
4 patients
Outcome
Evolution of skin involvement by CDASI-A
Methodological detailsrefractory patients
  • Refractory patients

Main finding

As reported in the abstract

CDASI-A, mean (scale /100)

Observational data: associations, not effects.

Further findings

MMT-8, mean (scale /80)

OutcomeEnrollmentAfter treatment
Daily GC dose (prednisone), meanmean 10 mg4 mg
PtGA, mean (scale /10)mean 7.5 /101.5 /10

Original publication

Anifrolumab Therapy in Dermatomyositis: New Insights From Refractory Patients. J Rheumatol. Published 1 November 2025. doi:10.3899/jrheum.2025-0773

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