Nailfold capillaroscopy findings of a multicentric multi-ethnic cohort of patients with idiopathic inflammatory myopathies
Authors' conclusion
NVC abnormalities are related to the diagnosis, clinical features, disease activity, and autoantibodies of patients with IIM.
Study context
- Population
- Patients with idiopathic inflammatory myopathies (IIM) from three centres in Mexico, Spain and the USA23 with follow-up nailfold video capillaroscopic (NVC)
- Participants
- 155 patients
- Outcome
- NVC abnormalities and their association with clinical features, myositis-specific autoantibodies (MSA) and myositis-associated antibodies (MAA)
Methodological detailsmulticentre, multi-ethnic, semiquantitative and quantitative NVC analysis
- Multicentre
- Multi-ethnic
- Semiquantitative and quantitative NVC analysis
Main finding
As reported in the abstract
NVC patterns
Normal NVC
14
9%
Non-specific abnormality pattern (most frequent); associated with joint involvement, ILD, Jo1 autoantibodies, anti-synthetase syndrome and IMNM
53.9%
Observational data: associations, not effects.
Further findings
NVC changes after treatment (follow-up NVC at disease control)
- Decrease in capillaroscopic score, capillary diameter and number of avascular areas; increase in capillary density and bushy capillary number
Original publication
Nailfold capillaroscopy findings of a multicentric multi-ethnic cohort of patients with idiopathic inflammatory myopathies. Clin Exp Rheumatol. Published 14 March 2024. doi:10.
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