Musculoskeletal Ultrasound in Childhood Arthritis Limited Examination: A Comprehensive, Reliable, Time‐Efficient Assessment of Synovitis
Authors' conclusion
A limited MSUS examination called musculoskeletal ultrasound in childhood arthritis limited examination (MUSICAL) captures all patients with active synovitis, and our new joint-specific scoring system is highly reliable and sensitive to change.
Study context
- Population
- Newly diagnosed JIA patients with an active joint count of >4
- Participants
- 30 participants
- Comparison
- 42-joint musculoskeletal ultrasound (MSUS) vs reduced 5-joint bilateral MSUS
- Outcome
- Interrater reliability of the joint-specific MSUS scoring system and minimum number of joints needed to identify active disease
Methodological detailsconsensus-developed semiquantitative scoring system, interrater reliability (intraclass correlation coefficients (ICCs)), data reduction process
- Consensus-developed semiquantitative scoring system
- Interrater reliability (ICCs)
- Data reduction process
Performance
As reported in the abstract
| Test or model | Value | Children with B-mode synovitis captured |
|---|---|---|
| Reduced joints | 100% | 100% |
Reduced joints
Value100%
Children with B-mode synovitis captured100%
- Interrater reliability (ICC) for all joints, excellent
- 0.81-0.96
Further findings
Correlation of reduced joints MSUS with cJADAS10 · baseline
- Spearman rs, moderate correlation
- 0.45
Mean ultrasound score, baseline and follow-up; SRM · baseline and 3 months
- 42 joints: mean score baseline
- 28.3
- 42 joints: mean score follow-up
- 22.3
- 42 joints: SRM (P = 0.002)
- 0.69
- Reduced joints: mean score baseline
- 36
- Reduced joints: mean score follow-up
- 27.7
- Reduced joints: SRM (P = 0.003)
- 0.76
Original publication
Musculoskeletal Ultrasound in Childhood Arthritis Limited Examination: A Comprehensive, Reliable, Time‐Efficient Assessment of Synovitis. Arthritis Care Res (Hoboken). Published 13 September 2022. doi:10.
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