Musculoskeletal symptoms and their impact on health-related quality of life in chronic nonbacterial osteomyelitis patients
Authors' conclusion
MSK manifestations have a negative impact on HRQoL in CNO patients.
Study context
- Population
- Children and adults with CNO diagnosed before the age of 18, and their parents; malignancy or prior chronic rheumatic, musculoskeletal (MSK) or neurological disease excluded66.2% female
- Participants
- 68 children
- Exposure
- Patients with MSK manifestations vs patients without
- MSK manifestationsn = 45
- Outcome
- Correlation between MSK symptoms (Nordic MSK Questionnaire) and HRQoL (PedsQL-4 and PedsQL rheumatology module)
Methodological detailsweb-based survey
- Web-based survey
Main finding
As reported in the abstract
HRQoL scores, MSK manifestations vs without
- Patients with MSK manifestations had lower health-related quality of life (HRQoL) scores than patients without
- MSK manifestations vs No MSK manifestations: P < 0.001
- MSK manifestations vs No MSK manifestations: P < 0.001
- MSK manifestations vs No MSK manifestations: P = 0.033
- MSK manifestations vs No MSK manifestations: P < 0.001
- MSK manifestations vs No MSK manifestations: P = 0.007
- MSK manifestations vs No MSK manifestations: P < 0.001
- MSK manifestations vs No MSK manifestations: P < 0.001
- MSK manifestations vs No MSK manifestations: P < 0.001
- MSK manifestations vs No MSK manifestations: P = 0.035
- MSK manifestations vs No MSK manifestations: P = 0.001
- MSK manifestations vs No MSK manifestations: P < 0.001
Observational data: associations, not effects.
Further findings
- Prevalence of MSK manifestations at the last month
- 66.2% · 45
- Prevalence of MSK manifestations at the last month — Most commonly affected part: ankle and feet
- 26.5%
Original publication
Musculoskeletal symptoms and their impact on health-related quality of life in chronic nonbacterial osteomyelitis patients. Pediatr Rheumatol Online J. Published 6 March 2024. doi:10.
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