Vasculitis & polymyalgia rheumatica
Magnetic Resonance Vasculitis Activity Score (MRVAS)—introducing a standardized magnetic resonance scoring system for assessing the extent of inflammatory burden in giant cell arteritis
Authors' conclusion
The proposed MRVAS allows standardized scoring of inflammation in GCA and achieved high agreement rates in a prospective setting.
Study context
- Population
- Patients with suspected GCA undergoing MRI of the cranial arteries and the aorta and its branches (20 vessel segments)suspected GCA
- Participants
- 80 patients
- Exposure
- Experienced radiologists vs inexperienced radiologists applying the MRVAS
- Outcome
- Interrater reliability of the MRVAS (ICC; Cohen's κ for individual vessel segments)
Methodological detailsblinded readers, prospective
- Blinded readers
- Prospective
Main finding
As reported in the abstract
Interrater reliability of the MRVAS
- ICC, individual vessel-based level, GCA
- 0.95
- ICC, individual vessel-based level, non-GCA
- 0.96
- ICC, overall MRVAS level, GCA
- 0.96
- ICC, overall MRVAS level, non-GCA
- 1.0
- Cohen's κ range, all reader pairs (significant concordance, P < 0.001)
- 0.78-0.98
Observational data: associations, not effects.
Original publication
MRVAS—introducing a standardized magnetic resonance scoring system for assessing the extent of inflammatory burden in giant cell arteritis. Rheumatology (Oxford). Published 1 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →