Lupus & antiphospholipid syndrome
Maternal and fetal outcomes in pregnant patients with systemic lupus erythematosus: A study from a Latin American developing country
Authors' conclusion
This study associates preterm delivery with factors such as proteinuria >1 g, shorter disease duration, and a moderate to severe score in the second trimester of pregnancy.
Study context
- Population
- Pregnant women with SLE, a hospital in Bogotá, Colombia, 1/January/2012 to 29/February/2024
- Participants
- 28 women29 pregnancies
- Outcome
- Factors associated with obstetric outcomes (e.g. preterm delivery)
Methodological detailsdescriptive, single hospital, Approved by the Ethics Committee
- Descriptive
- Single hospital
- Approved by the Ethics Committee
Main finding
As reported in the abstract
Moderate to severe SLEPDAI score in the second and third trimester
83%
p = .04
Shorter disease duration (months)
24 vs 96 months
p = .027
Proteinuria >1 g
40.91%
p = .03
Observational data: associations, not effects.
Further findings
Patient characteristics
- Median age (years)
- 28
- Median disease duration (months)
- 60
- Poly-autoimmunity
- Twenty percent
- Overall disease activity mild to moderate
Original publication
Maternal and fetal outcomes in pregnant patients with systemic lupus erythematosus: A study from a Latin American developing country. Lupus. Published 30 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →