Lupus & antiphospholipid syndrome
Maternal and fetal health outcomes in systemic lupus erythematosus pregnancies in the Emirati population: A comparative study
Authors' conclusion
Pregnant women with SLE were at a higher risk for adverse maternal and fetal outcomes than age-matched pregnant women without SLE.
Study context
- Population
- Emirati women with systemic lupus erythematosus (SLE) and a history of pregnancy, Tawam Hospital78 SLE pregnancies in 39 women
- Participants
- 78 SLE pregnancies
- Exposure
- SLE pregnancies vs age-matched pregnant women without SLE
- SLEn = 78
- Outcome
- Adverse maternal and fetal pregnancy outcomes
Methodological detailsone-to-one age-matched healthy control group, single-centre
- One-to-one age-matched healthy control group
- Single-centre
Main finding
As reported in the abstract
Adverse pregnancy outcomes
Adverse maternal outcomes (e.g. Gestational diabetes mellitus (GDM)) in SLE pregnancies
32%
Adverse fetal outcomes (e.g. low-birth weight, preterm deliveries) in SLE pregnancies
51%
Observational data: associations, not effects.
Further findings
Factors associated with adverse outcomes
- Steroid use during pregnancy significantly associated with increased risk of GDM
- LN, maternal hypertension, pre-eclampsia and GDM linked to preterm deliveries
Original publication
Maternal and fetal health outcomes in systemic lupus erythematosus pregnancies in the Emirati population: A comparative study. Lupus. Published 2 October 2023. doi:10. 1177/ 09612033231204650
Composed by AI from the published abstract and checked against it. How Briefs are made →