Lupus & antiphospholipid syndrome

Maternal and fetal health outcomes in systemic lupus erythematosus pregnancies in the Emirati population: A comparative study

LupusPublished Retrospective cohort study

Authors' conclusion

Pregnant women with SLE were at a higher risk for adverse maternal and fetal outcomes than age-matched pregnant women without SLE.

Study context

Population
Emirati women with systemic lupus erythematosus (SLE) and a history of pregnancy, Tawam Hospital78 SLE pregnancies in 39 women
Participants
78 SLE pregnancies
Exposure
SLE pregnancies vs age-matched pregnant women without SLE
  • SLEn = 78
Outcome
Adverse maternal and fetal pregnancy outcomes
Methodological detailsone-to-one age-matched healthy control group, single-centre
  • One-to-one age-matched healthy control group
  • Single-centre

Main finding

As reported in the abstract

Adverse pregnancy outcomes

Adverse maternal outcomes (e.g. Gestational diabetes mellitus (GDM)) in SLE pregnancies

32%

Adverse fetal outcomes (e.g. low-birth weight, preterm deliveries) in SLE pregnancies

51%

Observational data: associations, not effects.

Further findings

Factors associated with adverse outcomes

Steroid use during pregnancy significantly associated with increased risk of GDM
LN, maternal hypertension, pre-eclampsia and GDM linked to preterm deliveries

Original publication

Maternal and fetal health outcomes in systemic lupus erythematosus pregnancies in the Emirati population: A comparative study. Lupus. Published 2 October 2023. doi:10.1177/09612033231204650

Composed by AI from the published abstract and checked against it. How Briefs are made →

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