Lupus & antiphospholipid syndrome
Infection vulnerability in pregnant women with and without systemic lupus erythematosus
Authors' conclusion
The risks of infection and adverse outcomes are significantly higher in pregnant women with SLE than in the non-SLE population.
Study context
- Population
- Emirati women with SLE pregnant between January 2010 and August 2023 and age-matched women without SLE, Tawam Hospital, Abu Dhabi, United Arab Emirates87 pregnancies in 41 women with SLE
- Exposure
- Pregnant women with SLE vs age-matched women without SLE
- Outcome
- Infection during pregnancy
Methodological detailsage-matched control group, univariate and multivariate regression analyses
- Age-matched control group
- Univariate and multivariate regression analyses
Main finding
As reported in the abstract
Infection rate during pregnancy
Observational data: associations, not effects.
Further findings
Adverse fetal outcomes
Maternal outcomes
Adverse fetal outcomes
- Significantly higher in the SLE group than in the control group
Maternal outcomes
- Significantly higher in the SLE group than in the control group
Factors associated with infection risk in pregnant women with SLE
- Respiratory infections were the most prevalent infection type
- No variable was found to increase the risk of infection
- HCQ use during pregnancy significantly associated with a reduced risk of infection
Mean age at conception
- Higher in women with SLE than in the control group
Original publication
Infection vulnerability in pregnant women with and without systemic lupus erythematosus. Lupus. Published 21 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →