Spondyloarthritis & psoriatic arthritis

Machine Learning Pipeline for Predicting Bone Marrow Edema Along the Sacroiliac Joints on Magnetic Resonance Imaging

Arthritis RheumatolPublished Diagnostic accuracy study

Authors' conclusion

We propose a fully automated ML pipeline that enables objective and standardized evaluation of BME along the SI joints on MRI.

Study context

Population
Patients with spondyloarthritis (SpA), postpartum individuals and healthy subjects with sacroiliac (SI) joint magnetic resonance imaging (MRI) (semicoronal T1/T2-weighted)
Comparison
Cross-validation vs Test data set
  • Test data setn = 243
Outcome
Prediction of bone marrow edema (BME) on a quadrant level in SI joint MRI, vs ground truth by consensus of human readers
Methodological detailsfully automated machine learning pipeline, ResNet18 backbone, five-fold cross-validation, independent test data set
  • Fully automated machine learning pipeline
  • ResNet18 backbone
  • Five-fold cross-validation
  • Independent test data set

Performance

As reported in the abstract

Quadrant-level BME prediction
Test or modelAUCBalanced accuracyF1 score
Cross-validation94.5%80.5%64.1%
Test data set88.2%72.1%50.8%

AUC

Cross-validation94.5%
Test data set88.2%

Balanced accuracy

Cross-validation80.5%
Test data set72.1%

F1 score

Cross-validation64.1%
Test data set50.8%

Further findings

Patient-level BME prediction (≥1 positive quadrant)

Balanced accuracy

SI joint detection and ilium/sacrum segmentation

SI joint detection precision
98.4%
Ilium segmentation intersection over union
85.6%
Sacrum segmentation intersection over union
67.9%

Original publication

Machine Learning Pipeline for Predicting Bone Marrow Edema Along the Sacroiliac Joints on Magnetic Resonance Imaging. Arthritis Rheumatol. Published 10 November 2023. doi:10.1002/art.42650

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