Systemic sclerosis & Raynaud's
Lung ultrasound compared to computed tomography detection and automated quantification of systemic sclerosis-associated interstitial lung disease: preliminary study
Authors' conclusion
This preliminary study suggests the utility of a comprehensive LUS assessment for SSc-ILD detection compared with CT and QCT.
Study context
- Population
- Consecutive SSc patients (2013 ACR/EULAR criteria) with pulmonary functional tests (PFTs) and a CT within ± 6 months, 2021–2022
- Participants
- 29 patients
- Comparison
- Lung ultrasound (LUS) vs chest CT and automated QCT for SSc-ILD
- Outcome
- Association of LUS findings with ILD on CT and QCT
Methodological detailspreliminary study, consecutive patients, two certified blinded operators, 14-scans method
- Preliminary study
- Consecutive patients
- Two certified blinded operators
- 14-scans method
Performance
As reported in the abstract
- Both qualitative LUS scores significantly associated with ILD presence on CT; Fairchild's pleural line (PL) criteria slightly more accurate; confirmed on multivariate analysis
- All qualitative and quantitative LUS findings significantly associated with QCT ILD extension and radiological abnormalities
- Mid and basal PL quantitative score correlated with mid and basal QCT ILD extents
Further findings
Correlation with PFTs and clinical variables
- Both B-lines and PL alterations differently correlated with PFTs and clinical variables
Original publication
Lung ultrasound compared to computed tomography detection and automated quantification of systemic sclerosis-associated interstitial lung disease: preliminary study. Rheumatology (Oxford). Published 3 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →