Systemic sclerosis & Raynaud's
Comparison of quantitative lung ultrasound scores with automated quantitative CT: to overcome the ultrasound limitations
Authors' conclusion
Quantitative LUS score correlated with qCT-defined ILD extent, especially at lung bases. LUS scores (particularly the novel PLI score) were found to correlate with deeper ILD volume
Study context
- Population
- Consecutive SSc patients undergoing concurrent lung ultrasound (LUS) and CT scans, 2021–2023
- Participants
- 82 patients
- Exposure
- Quantitative LUS scores vs automated quantitative computed tomography (qCT) ILD extent
- Outcome
- Correlations between quantitative LUS scores (B-lines count, PLI score) and automated qCT ILD, GGO and RET volumes, including surface and core lung
Methodological detailsconsecutive patients, concurrent LUS and CT, automated quantitative CT texture analysis
- Consecutive patients
- Concurrent LUS and CT
- Automated quantitative CT texture analysis
Main finding
As reported in the abstract
Correlation of LUS scores with qCT volumes
- Total B-lines (BL) count and pleural line irregularity (PLI) score correlated with total ILD, ground-glass opacities (GGO) and reticulations (RET) volumes
- all P < 0.0001
- Total BL count and PLI score correlated with surface and core ILD volumes
- all P < 0.0001
- Basal lung BLs and PLI score correlated with basal ILD, GGO, RET and corresponding surface and core ILD volumes
- all P < 0.005
- Mid-lung PLI correlated with corresponding ILD-related changes and surface and core ILD
- all P < 0.005
Observational data: associations, not effects.
Original publication
Comparison of quantitative lung ultrasound scores with automated quantitative CT: to overcome the ultrasound limitations. Rheumatology (Oxford). Published 12 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →