Lupus & antiphospholipid syndrome

Limitations in Activities of Daily Living Among Individuals With Systemic Lupus Erythematosus

Arthritis Care Res (Hoboken)Published Cross-sectional study

Authors' conclusion

IADL and BADL limitations may be common in individuals with SLE and more prevalent among those who report higher disease activity, depressive symptoms, and lower income and among those who are older.

Study context

Population
Individuals with systemic lupus erythematosus (SLE) recruited from a population-based cohort (October 2019 to May 2022); mean age 46.2 years, 91.7% female, 82.8% Black
Participants
436 individuals
Outcome
Limitations in IADLs and BADLs (at least some difficulty performing at least one IADL or BADL)
Methodological detailspopulation-based cohort, survey, logistic regression adjusted for age, sex and race
  • Population-based cohort
  • Survey
  • Logistic regression adjusted for age, sex and race

Main finding

As reported in the abstract

Prevalence of ADL limitations
Limitations in instrumental ADLs (IADLs)
56.2%
IADL: housekeeping
50.7%
IADL: laundry
37.2%
IADL: shopping
33.0%
Limitations in basic ADLs (BADLs)
43.8%
BADL: transferring
26.6%
BADL: bathing
25.3%
BADL: dressing
24.4%
BADL: continence
22.0%

Observational data: associations, not effects.

Further findings

OutcomeaOR (95% CI)
Higher disease activity (≥ vs < median) and ADL limitationsHigher disease activity (≥ median)vs < medianIADLs6.49 (4.15–10.2)
Higher disease activity (≥ vs < median) and ADL limitationsHigher disease activity (≥ median)vs < medianBADLs7.35 (4.70–11.5)

Higher disease activity (≥ vs < median) and ADL limitations

Also associated: higher depression and perceived stress scores, lower educational attainment and income, older age

Original publication

Limitations in Activities of Daily Living Among Individuals With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). Published 10 November 2024. doi:10.1002/acr.25446

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