Vasculitis & polymyalgia rheumatica
Left ventricular assessment using speckle-tracking echocardiography in Behçet's disease: a systematic review and meta-analysis
Pooled result · LV GLSResult — go to the resultSMD −0.59 95% CI −1.21 to 0.04Authors' conclusion
BD patients do not exhibit consistent subclinical LV systolic dysfunction in strain echocardiography. Further studies are required to optimise the use of STE in this population.
Study context
- Population
- Studies assessing left ventricular (LV) strain by speckle tracking echocardiography (STE) in Behçet's disease (BD) patients and controlsEight studies including 373 BD patients and 402 controls
- Participants
- 373 vs 402
- Comparison
- LV global longitudinal strain (GLS) between BD patients and controls
- BDn = 373
- CONTROLSn = 402
- Outcome
- LV GLS
Methodological detailsrandom-effects models, two- or four-dimensional STE, Baujat plot and leave-one-out analysis
- Random-effects models
- Two- or four-dimensional STE
- Baujat plot and leave-one-out analysis
Pooled result
As reported in the abstract
SMD
−0.59
95% CI −1.21 to 0.04
P = 0.06
BDvs CONTROLS
SMD −0.59 (95% CI −1.21 to 0.04); P = 0.06
Further pooled results
| Outcome | SMD (95% CI) | |
|---|---|---|
| LV GLS, subgroup of patients with non-active disease | −0.9 (−1.71 to −0.08) | |
| −2−101Difference (linear scale) |
- LV GLS, subgroup of patients with non-active disease: GLS impairment more pronounced in patients with non-active disease
LV GLS, subgroup of patients with no cardiovascular risk factors
- No significant difference (p=0.20)
- P = 0.20
Original publication
Left ventricular assessment using speckle-tracking echocardiography in Behçet's disease: a systematic review and meta-analysis. Clin Exp Rheumatol. Published 26 October 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →