Autoinflammatory & rare systemic diseases
Laryngeal involvement in relapsing polychondritis: clinical and CT findings in 173 patients
Authors' conclusion
Laryngeal involvement is common in RP patients with airway manifestations, second only to tracheal involvement. CT findings of cricoid erosion and broadening are characteristic.
Study context
- Population
- Patients with confirmed relapsing polychondritis (RP)
- Participants
- 173 patients
- Outcome
- Clinical features and CT findings of laryngeal involvement in RP
Main finding
As reported in the abstract
CT evidence of airway involvement
Asymptomatic patients with CT evidence of airway damage
66%
Laryngeal involvement
41.1%
44/107
Tracheal involvement
80.9%
140/173
Bronchial involvement
36.4%
63/107
Observational data: associations, not effects.
Further findings
Factors associated with laryngeal involvement
- Younger age at disease onset
- P < 0.05
- Longer disease duration
- P < 0.01
- Multiorgan manifestations
- P < 0.01
Original publication
Laryngeal involvement in relapsing polychondritis: clinical and CT findings in 173 patients. RMD Open. Published 8 May 2025. doi:10. 1136/ rmdopen-2024-005397
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