Sjögren's disease & overlap diseases

Lacrimal gland ultrasonography shows superior reliability of OMERACT colour Doppler scoring compared to B-mode, in patients with clinically suspected Sjögren’s disease

Scand J RheumatolPublished Reliability study

Authors' conclusion

This study, performing LGUS in patients with clinically suspected SjD, shows that the reliability of B-mode ultrasound may be a concern. The reliability of OMERACT CDUS is superior to Hocevar and OMERACT B-mode scoring of the LGs.

Study context

Population
Consecutive patients with clinically suspected Sjögren's disease (SjD) (28 diagnosed with SjD, 13 non-SjD)
Participants
40 / 40 / 31
Comparison
Hocevar vs OMERACT B-mode vs OMERACT colour Doppler ultrasound (CDUS) scoring of lacrimal gland ultrasound
  • Hocevarn = 40
  • OMERACT B-moden = 40
  • OMERACT CDUSn = 31
Outcome
Intra- and interobserver reliability (ICC) of lacrimal gland ultrasound (LGUS) scoring systems
Methodological detailsconsecutive patients, four blinded observers, two scoring sessions
  • Consecutive patients
  • Four blinded observers
  • Two scoring sessions

Main finding

As reported in the abstract

Intra- and interobserver reliability (ICC)
GroupIntraobserver ICC (fair to moderate)Interobserver ICC session 1 (fair)Interobserver ICC session 2 (fair)Interobserver ICC session 1 (poor to fair)Interobserver ICC session 2 (poor to fair)Intraobserver ICC (good)Interobserver ICC session 1 (good)Interobserver ICC session 2 (good)
Hocevar0.34 to 0.500.310.25— not stated in the abstract— not stated in the abstract— not stated in the abstract— not stated in the abstract— not stated in the abstract
OMERACT B-mode0.27 to 0.54— not stated in the abstract— not stated in the abstract0.230.16— not stated in the abstract— not stated in the abstract— not stated in the abstract
OMERACT CDUS— not stated in the abstract— not stated in the abstract— not stated in the abstract— not stated in the abstract— not stated in the abstract0.61 to 0.800.630.69

Intraobserver ICC (fair to moderate)

Hocevar0.34 to 0.50
OMERACT B-mode0.27 to 0.54
OMERACT CDUS— not stated in the abstract

Interobserver ICC session 1 (fair)

Hocevar0.31
OMERACT B-mode— not stated in the abstract
OMERACT CDUS— not stated in the abstract

Interobserver ICC session 2 (fair)

Hocevar0.25
OMERACT B-mode— not stated in the abstract
OMERACT CDUS— not stated in the abstract

Interobserver ICC session 1 (poor to fair)

Hocevar— not stated in the abstract
OMERACT B-mode0.23
OMERACT CDUS— not stated in the abstract

Interobserver ICC session 2 (poor to fair)

Hocevar— not stated in the abstract
OMERACT B-mode0.16
OMERACT CDUS— not stated in the abstract

Intraobserver ICC (good)

Hocevar— not stated in the abstract
OMERACT B-mode— not stated in the abstract
OMERACT CDUS0.61 to 0.80

Interobserver ICC session 1 (good)

Hocevar— not stated in the abstract
OMERACT B-mode— not stated in the abstract
OMERACT CDUS0.63

Interobserver ICC session 2 (good)

Hocevar— not stated in the abstract
OMERACT B-mode— not stated in the abstract
OMERACT CDUS0.69

— not stated in the abstract

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Lacrimal gland ultrasonography shows superior reliability of OMERACT colour Doppler scoring compared to B-mode, in patients with clinically suspected Sjögren’s disease. Scand J Rheumatol. Published 9 September 2025. doi:10.1080/03009742.2025.2548668

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