Joint distraction using a purpose-built device for knee osteoarthritis: a prospective 2-year follow-up
Authors' conclusion
Patients treated with a general applicable, for knee distraction purpose-built device showed, despite adverse events, significant clinical and structural improvement over 2 years.
Study context
- Population
- Patients (≤65 years) with end-stage knee OA indicated for arthroplasty49 completed 2-year follow-up
- Participants
- 65 patients
- Outcome
- Total WOMAC score, change from baseline
- Follow-up
- 1 and 2 years
Methodological detailssingle-group, 2-year follow-up, one patient did not complete treatment, Eight patients were lost to follow-up in the second year
- Single-group
- 2-year follow-up
- One patient did not complete treatment
- Eight patients were lost to follow-up in the second year
Main finding
As reported in the abstract
- Total WOMAC improvement at 1 year (points)
- +26
- Total WOMAC improvement at 2 years (points)
- +24
- All subscales improved
- p<0.001
Observational data: associations, not effects.
Further findings
Minimum radiographic joint space width, change · 1 and 2 years
- Change at 1 year
- +0.5 mm; p<0.001
- Change at 2 years
- +0.4 mm; p=0.015
Physical Short-Form 36, change
- Improvement (points)
- +10 points; p<0.001
Pain medication use
- Before treatment
- 42%
- 1 year post-treatment
- 23%; p=0.02
- 2 years post-treatment
- 29%; p=0.27
Arthroplasty during follow-up
- Arthroplasty in first year
- 3
- Arthroplasty in second year
- 4
Safety
Pin tract infection (most common adverse event)
- Patients experiencing pin tract infection
- 66%
- Successfully treated with oral antibiotics
- 88%
- Cases needing hospitalisation and/or IV antibiotics
- 2
Device-related complications
- Patients with device-related complications
- 8
- None of the complications influenced 2-year outcomes
Original publication
Joint distraction using a purpose-built device for knee osteoarthritis: a prospective 2-year follow-up. RMD Open. Published 8 June 2023. doi:10.
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