Examining the influence of pain neuroscience education followed by a Pilates exercises program in individuals with knee osteoarthritis: a pilot randomized controlled trial
Primary result · WOMAC painResult — go to the resultAdjusted mean difference −0.8 95% CI −2.2 to 0.7Authors' conclusion
Combining PNE with PEs could have superior effects on psychological characteristics but not on pain, physical limitation, and function, compared to PEs alone.
Study context
- Population
- Community-dwelling adults with knee osteoarthritis (OA), university health center
- Participants
- 54 adults
- Comparison
- Pain neuroscience education followed by Pilates exercises vs Pilates exercises alone
- Pain neuroscience education (PNE) + Pilates exercises (PEs)n = 27
- PEsn = 27reference
- Primary endpoint
- WOMAC subscales of pain and physical limitation
- Follow-up
- Eight weeks post-treatment
Methodological detailspilot, two-arm, assessor-blind, July 2021 to March 2022, university health center
- Pilot
- Two-arm
- Assessor-blind
- July 2021 to March 2022, university health center
Primary result
WOMAC pain · eight weeks
Adjusted mean difference
−0.8
95% CI −2.2 to 0.7
P = 0.288
PNE + PEsvs PEs
adjusted mean difference −0.8 (95% CI −2.2 to 0.7); P = 0.288
As reported in the abstract
Secondary outcomes
| Outcome | Adjusted mean difference (95% CI) | P value | |
|---|---|---|---|
| Co-primary: WOMAC physical limitation · eight weeks | −0.4 (−4 to 3.1) | P = 0.812 | |
| Function (Timed Up & Go) · eight weeks | −0.8 (−1.8 to 0.1) | P = 0.069 | |
| Pain catastrophizing · post-treatmentFavoring PNE followed by PEs | −3.9 (−7.2 to −0.6) | P = 0.021 | |
| Kinesiophobia · post-treatmentFavoring PNE followed by PEs | −4.2 (−8.1 to −0.4) | P = 0.032 | |
| Pain self-efficacy · post-treatmentFavoring PNE followed by PEs | 6.1 (0.7–11.5) | P = 0.028 | |
| −10−5051015Difference (linear scale) |
Original publication
Examining the influence of pain neuroscience education followed by a Pilates exercises program in individuals with knee osteoarthritis: a pilot randomized controlled trial. Arthritis Res Ther. Published 6 June 2023. doi:10.
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