Efficacy of a Very-Low-Calorie Weight Loss Diet Plus Exercise Compared With Exercise Alone on Hip Osteoarthritis Pain : A Randomized Controlled Trial
Primary result · Change in hip pain severityResult — go to the resultMean difference −0.6 units 95% CI −1.5 to 0.3Authors' conclusion
Adding a weight loss diet to exercise did not change hip pain but improved most secondary outcomes.
Study context
- Population
- Adults with hip OA and overweight or obesity, community setting99 (98%) with 6-month primary outcome
- Participants
- 101 adults
- Comparison
- Very-low-calorie diet (VLCD) plus exercise vs exercise only
- Primary endpoint
- Change in hip pain severity (11-point scale, 0 to 10, higher worse; MCID 1.8)
- Follow-up
- 6 months
Methodological details2-group, superiority, participants unblinded
- 2-group
- Superiority
- Participants unblinded
Primary result
Change in hip pain severity
Mean difference
−0.6 units
95% CI −1.5 to 0.3
VLCD plus exercisevs Exercise only
mean difference −0.6 units (95% CI −1.5 to 0.3)
As reported in the abstract
Secondary outcomes
Weight loss
- VLCD plus exercise lost more weight than exercise only
- 8.5%
Other secondary outcomes · 6 months
- Between-group differences favored VLCD plus exercise except HOOS pain and function
Secondary outcomes · 12 months
- Weight, BMI, HOOS pain and function, and overall hip improvement, but not quality of life and physical activity, favored VLCD plus exercise
- 95 (94%) provided 12-month primary outcome
Safety
Serious related adverse events
- None
- 0
Original publication
Efficacy of a Very-Low-Calorie Weight Loss Diet Plus Exercise Compared With Exercise Alone on Hip Osteoarthritis Pain : A Randomized Controlled Trial. Ann Intern Med. Published 5 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →