Osteoarthritis

Prevalence of osteosarcopenia in patients with end-stage knee osteoarthritis (OA) who underwent total knee arthroplasty

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Osteosarcopenia was present in 24.1% of patients with end-stage knee OA undergoing TKA, exceeding rates in the general population.

Study context

Population
Patients with end-stage knee OA who underwent total knee arthroplasty (TKA), April 2022 to May 2023mean age 73.5 ± 6.8 years
Participants
1,755 patients
Exposure
Women vs men
  • Womenn = 1,554
Outcome
Prevalence of osteoporosis and sarcopenia (osteosarcopenia); preoperative appendicular lean mass index and BMD by DXA
Follow-up
Preoperative

Main finding

As reported in the abstract

Osteosarcopenia prevalence
Osteosarcopenia, all patients
24.1%

Observational data: associations, not effects.

Further findings

Osteoporosis prevalence

Sarcopenia prevalence

Osteoporosis prevalence

Significantly higher in women than in men

Sarcopenia prevalence

Significantly higher in women than in men

Original publication

Prevalence of osteosarcopenia in patients with end-stage knee OA who underwent total knee arthroplasty. Osteoporos Int. Published 31 October 2025. doi:10.1007/s00198-025-07731-7

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