Individual and Socioecological Resilience in Childhood-Onset Systemic Lupus Erythematosus: Associations With Patient Characteristics and Psychosocial Patient-Reported Outcomes
Authors' conclusion
Greater resilience was associated with fewer ACEs and better health-related communication, patient-reported mental health, and executive functioning.
Study context
- Population
- Patients with cSLE, ages 11–22 years, Canadian tertiary center, October 2021 to July 2024
- Participants
- 49 patients
- Outcome
- Individual resilience (CD-RISC-10) and socioecological resilience (CYRM-R) and their associations with sociodemographic and disease characteristics and psychosocial patient-reported outcome measures (PROMs)
Methodological detailssingle-centre (Canadian tertiary center), linear regression, Pearson correlations
- Single-centre (Canadian tertiary center)
- Linear regression
- Pearson correlations
Main finding
As reported in the abstract
- Individual psychological resilience (Connor-Davidson Resilience Scale (CD-RISC-10)), mean (SD)
- 26.0 (SD 7.1)
- Socioecological resilience (Child and Youth Resilience Measure-Revised (CYRM-R)), mean (SD)
- 73.4 (SD 9.1)
- Higher CD-RISC-10 associated with better health literacy (communication subscale), β
- 0.99 (0.45-1.55), P < 0.01 (95% CI)
- Higher CYRM-R associated with better health literacy (communication subscale), β
- 0.84 (0.13-1.55), P = 0.02 (95% CI)
- Lower CYRM-R associated with higher number of ACEs, β
- −1.02 (−1.88 to −0.17), P = 0.02 (95% CI)
- CD-RISC-10 correlation with worse depressive symptoms, r
- −0.44, P = 0.003
- CYRM-R correlation with worse depressive symptoms, r
- −0.55, P = 0.001
- CD-RISC-10 correlation with worse executive functioning, r
- −0.49, P = 0.002
- CYRM-R correlation with worse executive functioning, r
- −0.56, P = 0.002
Observational data: associations, not effects.
Original publication
Individual and Socioecological Resilience in Childhood-Onset Systemic Lupus Erythematosus: Associations With Patient Characteristics and Psychosocial Patient-Reported Outcomes. J Rheumatol. Published 1 September 2025. doi:10.
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