Spondyloarthritis & psoriatic arthritis

Incidence Rate and Factors Associated With Fractures Among Medicare Beneficiaries With Ankylosing Spondylitis in the United States

Arthritis Care Res (Hoboken)Published Retrospective cohort study

Authors' conclusion

In this large sample of Medicare beneficiaries with AS, increasing age, historical fracture, and use of opioids had higher odds of fracture. Men and women were equally likely to have a fracture.

Study context

Population
Adults with prevalent AS, RISE registry linked to Medicare claims, 2016–2018 (mean age 69.4 years; 44.3% female)197 with fractures
Participants
1,426 adults
Outcome
Incidence rate of fractures
Methodological detailsregistry linked to Medicare claims, logistic regression
  • Registry linked to Medicare claims
  • Logistic regression

Main finding

As reported in the abstract

Overall incidence rate of fractures per 1,000 person-years

76.7

95% CI 66.4–88.6

Observational data: associations, not effects.

Further findings

Factors associated with fracture (logistic regression)

OR (95% CI)
Older age2.8 (1.39–5.65)
Historical fracture5.24 (3.44–7.99)
Use of >30 mg morphine equivalent1.86 (1.08–3.19)

Original publication

Incidence Rate and Factors Associated With Fractures Among Medicare Beneficiaries With Ankylosing Spondylitis in the United States. Arthritis Care Res (Hoboken). Published 30 October 2023. doi:10.1002/acr.25219

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