Vasculitis & polymyalgia rheumatica
Incidence of systemic vasculitides after Mycobacterium tuberculosis infection: a population-based cohort study in Korea
Main finding · SVResult — go to the resultAdjusted hazard ratio 1.72 95% CI 1.45–2.05Authors' conclusion
Patients with TB have an increased risk of SV, which is prominent in extrapulmonary TB.
Study context
- Population
- South Korean National Claims database: patients with tuberculosis (TB) and controls who had undergone appendectomymean follow-up 7.5 years
- Participants
- 418,677 vs 160,289
- Exposure
- TB vs controls
- TBn = 418,677
- Controlsn = 160,289reference
- Outcome
- Incidence of systemic vasculitides (SV)
Methodological detailspopulation-based, national claims database, adjusted Cox proportional hazards regression, stabilized inverse probability of treatment weighting sensitivity analysis
- Population-based
- National claims database
- Adjusted Cox proportional hazards regression
- Stabilized inverse probability of treatment weighting sensitivity analysis
Main finding
SV
Adjusted hazard ratio
1.72
95% CI 1.45–2.05
TBvs Controls
aHR 1.72 (95% CI 1.45–2.05)
As reported in the abstract
- Overall systemic vasculitides (SV) incidence rate
- 192/1 000 000 person-years
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| SV in extrapulmonary TB (subgroup)Extrapulmonary TBvs Controls | 4.28 (3.52–5.21) | |
| 0.20.5125Adjusted hazard ratio (log scale) |
Original publication
Incidence of systemic vasculitides after Mycobacterium tuberculosis infection: a population-based cohort study in Korea. Rheumatology (Oxford). Published 20 March 2024. doi:10.
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