Vasculitis & polymyalgia rheumatica
Concordance and agreement between different activity scores in polymyalgia rheumatica
Authors' conclusion
The correlation between all the PMR-ASs was excellent, reflecting the low weight of CRP.
Study context
- Population
- Patients with active PMR in the SEMAPHORE trial of tocilizumab vs placebo in PMR with GC dependence100 analysed
- Participants
- 101 patients
- Comparison
- Agreement between C reactive protein polymyalgia rheumatica activity score (CRP-PMR-AS), ESR-PMR-AS, clin-PMR-AS and imp-CRP-PMR-AS
- Primary endpoint
- Correlation of the PMR activity scores
Methodological detailspost hoc analysis, superiority, double-blind, placebo-controlled
- Post hoc analysis
- Superiority
- Double-blind
- Placebo-controlled
Primary result
As reported in the abstract
Correlation between the PMR-ASs (CRP-PMR-AS ≤10 or >10) · week 4 until week 24
ICC and kappa
>0.85
Secondary outcomes
Concordance of cut-off values, clin-PMR-AS vs CRP-PMR-AS
- Cut-off values similar, proportion of the time
- 86%
Original publication
Concordance and agreement between different activity scores in polymyalgia rheumatica. RMD Open. Published 15 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →