Vasculitis & polymyalgia rheumatica
Incidence and prevalence of granulomatosis with polyangiitis in Sweden, 2006–2019, a register-based study
Authors' conclusion
Our estimates show that incidence of GPA has been stable over the period 2006-2019 in Sweden which are in line with published data from southern Sweden.
Study context
- Population
- Entire Swedish population, 2006–2019; patients with incident and prevalent granulomatosis with polyangiitis (GPA) identified in the National Patient Registerincident GPA
- Participants
- 2,013 participants
- Outcome
- Age- and sex-standardised annual incidence and crude period prevalence of GPA
Methodological detailsnationwide, population-based, National Patient Register
- Nationwide
- Population-based
- National Patient Register
Main finding
As reported in the abstract
Mean standardised incidence of GPA · 2006–2019
- Mean standardised incidence per 100,000 person-years
- 1.9 (95% CI 1.8-2.0)
- Incidence in men per 100,000 person-years
- 2.0 (95% CI 1.9-2.2)
- Incidence in women per 100,000 person-years
- 1.7 (95% CI 1.6-1.8)
- Highest incidence, age 70-79, per 100,000 person-years (95% 3.7-4.5)
- 4.1
- Annual incidence stable over the study period, range
- 1.7-2.0
Observational data: associations, not effects.
Further findings
Point prevalence of GPA · 31 December 2019
- Point prevalence per 100,000 (95% CI 24.3-26.5); 2132 prevalent individuals
- 25.4
Period prevalence of GPA
- 2006-2010, per 100,000
- 18.7 (95% CI 17.8-19.1)
- 2016-2019, per 100,000
- 23.9 (95% CI 22.8-25.0)
Characteristics of incident GPA
- Median age, years (IQR 51-72)
- 63
- Women
- 46 %
Original publication
Incidence and prevalence of granulomatosis with polyangiitis in Sweden, 2006–2019, a register-based study. Semin Arthritis Rheum. Published 2 May 2025. doi:10.
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