Lupus & antiphospholipid syndrome

In-person versus virtual administration of the American College of Rheumatology gold standard cognitive battery in systemic lupus erythematosus: Are they interchangeable?

LupusPublished Retrospective analysis of a longitudinal cohort study

Authors' conclusion

Of the 19 tests in the ACR-NB, we identified one or more problems with eight (42%) tests when moving from in-person to virtual administration.

Study context

Population
Participants with systemic lupus erythematosus (SLE) in a longitudinal study of cognitive impairment, adapted during the COVID-19 pandemic328 SLE participants
Participants
801 visits
Exposure
In-person vs virtual administration of the modified ACR-neuropsychological battery (ACR-NB)
  • In-personn = 696reference
  • Virtualn = 105
Outcome
Cognitive performance and CI classification on the ACR-NB by administration method
Methodological detailsmulti-visit, intra-individual comparisons, retrospective preferences questionnaire
  • Multi-visit
  • Intra-individual comparisons
  • Retrospective preferences questionnaire

Main finding

As reported in the abstract

Cognitive performance across all three comparisons

Tests consistently statistically significantly different across all three comparisons

6

Participants whose CI classification changed

11 of 71

15%

Observational data: associations, not effects.

Further findings

Preferred administration method (retrospective questionnaire)

Baseline characteristics

Demographic, clinical and psychiatric characteristics comparable except ethnicity, anxiety and disease-related damage

Original publication

In-person versus virtual administration of the American College of Rheumatology gold standard cognitive battery in systemic lupus erythematosus: Are they interchangeable? Lupus. Published 10 April 2023. doi:10.1177/09612033231168477

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