Pediatric rheumatology

Impact of SARS-CoV-2 on the clinical presentation of juvenile idiopathic inflammatory myopathies

Pediatr Rheumatol Online JPublished Retrospective cohort study

Authors' conclusion

While our exploratory single-center study did not find significant differences in JIIM diagnosed pre- and post-pandemic

Study context

Population
Patients diagnosed with juvenile IIM (JIIM) before age 19 at The Children's Hospital at Montefiore
Participants
51 patients
Exposure
JIIM diagnosed post-COVID-19 vs pre-COVID-19
  • Post-COVID-19n = 13
Outcome
JIIM clinical presentation, post- vs pre-pandemic
Methodological detailssingle-centre, exploratory
  • Single-centre
  • Exploratory

Main finding

As reported in the abstract

  • Post-pandemic patients tended to be older, female, and have non-specific cutaneous manifestations (not statistically significant)
  • Fewer post-pandemic patients had delays in JIIM diagnosis

Observational data: associations, not effects.

Further findings

Known or suspected SARS-CoV-2 exposure among those with onset after January 1, 2020 — Post-COVID-19
60%
Post-COVID-19 patients with JIIM symptom onset after January 1, 2020
77% · 10 of 13

Original publication

Impact of SARS-CoV-2 on the clinical presentation of juvenile idiopathic inflammatory myopathies. Pediatr Rheumatol Online J. Published 11 August 2023. doi:10.1186/s12969-023-00861-4

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