Effects of Juvenile Idiopathic Inflammatory Myopathies on Growth, Development, and Maturation: A Systematic Review and Metaanalysis
Authors' conclusion
JIIM can cause several deleterious effects on development including growth failure.
Study context
- Population
- Children with juvenile idiopathic inflammatory myopathies (JIIM); studies in English from inception to December 202424 studies
- Outcome
- Effects of JIIM on growth and pubertal development
Methodological detailsInterrater reliability κ = 0.93 (abstract screening) and κ = 1.0 (full-text screening)
- Interrater reliability κ = 0.93 (abstract screening) and κ = 1.0 (full-text screening)
Pooled result
As reported in the abstract
Prevalence of growth failure (meta-analysis of 7 studies)
Overall prevalence of growth failure
17.90%
95% CI 10.74–25.06
Further pooled results
Growth
- Articles discussing growth
- 18
- Articles demonstrating decreased height or growth failure
- 14/18
Delays of secondary sex characteristics or puberty
- Articles reporting delays
- 5
Age of menarche onset
- Articles discussing age of menarche onset
- 5
- Articles reporting delays
- 4
- Articles not reporting delays
- 1
Original publication
Effects of Juvenile Idiopathic Inflammatory Myopathies on Growth, Development, and Maturation: A Systematic Review and Metaanalysis. J Rheumatol. Published 15 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →