Systemic sclerosis & Raynaud's
History of pre-eclampsia does not appear to be a risk factor for vascular phenotype in women with systemic sclerosis
Main finding · History of pre-eclampsiaResult — go to the resultOdds ratio 0.96 95% CI 0.28–3.34Authors' conclusion
In women with SSc and a pregnancy history≥6 months before SSc, a history of pre-eclampsia is not associated with a vascular phenotype.
Study context
- Population
- Adult women with systemic sclerosis (SSc) (EULAR 2013 criteria) and a pregnancy history ≥6 months before SSc diagnosis, 14 French hospital-based centres, July 2020 to July 2022
- Participants
- 378 women
- Comparison
- SSc with vascular phenotype vs SSc without
- Casesn = 129
- Controlsn = 249reference
- Outcome
- Personal history of pre-eclampsia before SSc diagnosis, per the validated pre-eclampsia questionnaire
Methodological detailsobservational, multicentre, matched controls
- Observational
- Multicentre
- Matched controls
Main finding
History of pre-eclampsia
Odds ratio
0.96
95% CI 0.28–3.34
P = 0.9
Events by group
Casesvs Controls
OR 0.96 (95% CI 0.28–3.34); P = 0.9
As reported in the abstract
Observational data: associations, not effects.
Further findings
Other risk factors for vascular phenotype
- Rodnan skin score and disease duration ≥5 years were risk factors for vascular phenotype
Original publication
History of pre-eclampsia does not appear to be a risk factor for vascular phenotype in women with systemic sclerosis. RMD Open. Published 4 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →