Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions for disease elements in calcium pyrophosphate crystal deposition (CPPD)
Methodological detailsDelphi exercise, 3-round Delphi exercise, based on systematic literature review
- Delphi exercise
- 3-round Delphi exercise
- Based on systematic literature review
Recommendations
As issued by the authors
'Calcium pyrophosphate (CPP) crystal' and 'calcium pyrophosphate crystal deposition (CPPD)' describe the deposition process
'Calcium pyrophosphate crystal deposition on imaging' as unified term across imaging modalities
'Chondrocalcinosis' redefined as conventional radiographic cartilage calcification consistent with CPPD
Four clinical manifestations: 'acute CPP crystal arthritis' ('flare' for acute episodes), 'chronic CPP crystal arthritis', 'crowned dens syndrome', and 'OA with CPPD'
The term 'pseudogout' received no support
Condition classified as 'asymptomatic CPPD' or 'CPPD disease' for symptomatic presentations
Original publication
Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions for disease elements in calcium pyrophosphate crystal deposition (CPPD). Ann Rheum Dis. Published 9 June 2026. doi:10.
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