Fibromyalgia & musculoskeletal pain

Global, regional and national temporal trends in prevalence for musculoskeletal disorders in women of childbearing age, 1990–2019: an age-period-cohort analysis based on the Global Burden of Disease Study 2019

Ann Rheum DisPublished Age-period-cohort analysis of Global Burden of Disease Study 2019 data

Authors' conclusion

Although a favourable overall temporal trend (net drift) of MSK disorders prevalence in WCBA was observed over the last 30 years globally, there were 138 countries showing unfavourable rising trends, coupled with deteriorations in period/cohort risks in many countries, collectively raising concerns about timely realisation of the Targets of Sustainable Development Goal.

Study context

Population
Women of childbearing age (WCBA) with musculoskeletal (MSK) disorders, global, regional and national levels, 1990–2019
Outcome
Temporal trends in prevalence of MSK disorders in WCBA: net drift (overall annual percentage change, % per year), local drift, age, period and cohort effects
Follow-up
1990–2019
Methodological detailsage-period-cohort model, global, regional and national estimates, 1990–2019
  • Age-period-cohort model
  • Global, regional and national estimates
  • 1990–2019

Main finding

As reported in the abstract

Global MSK disorders prevalence in WCBA
Global number of MSK disorders prevalence in WCBA in 2019
354.57 (million; 95% UI 322.64 to 387.68)
Global net drift 1990–2019
−0.06% (% per year; 95% CI −0.07% to −0.05%)
Net drift in low-middle sociodemographic index (SDI) region
−0.09% (% per year; 95% CI −0.10% to −0.07%)
Net drift in high-middle SDI region
0.10% (% per year; 95% CI 0.08% to 0.12%)
Countries presenting increasing trends
138
Countries presenting decreasing trends
24
Countries presenting relatively flat trends
42

Observational data: associations, not effects.

Further findings

Country-level prevalence in 2019

Countries with at least one million prevalence
50
Share of global prevalence in India, China, the USA, Indonesia and Brazil
51.03%

Local drift, age, period and cohort effects

Higher SDI regions had more age groups with rising prevalence; lower SDI regions more declining prevalence
Age effects similar across SDI regions, risk increasing with age
High SDI region generally lower period risks over time; others more unfavourable period risks
High, high-middle and middle SDI regions: unfavourable cohort deteriorations; others favourable improvements

Original publication

Global, regional and national temporal trends in prevalence for musculoskeletal disorders in women of childbearing age, 1990–2019: an age-period-cohort analysis based on the Global Burden of Disease Study 2019. Ann Rheum Dis. Published 2 January 2024. doi:10.1136/ard-2023-224530

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