Fibromyalgia & musculoskeletal pain

Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021

Lancet RheumatolPublished Systematic analysis of the Global Burden of Disease Study 2021

Authors' conclusion

Low back pain remains the leading cause of YLDs globally, and in 2020, there were more than half a billion prevalent cases of low back pain worldwide.

Study context

Population
Global population, 204 countries and territories, 1990–2020; low back pain defined as pain between the 12th ribs and the gluteal folds lasting a day or more204 countries and territories
Outcome
Prevalence and YLDs for low back pain
Methodological detailsnested Bayesian meta-regression, network meta-regression for alternative definitions, projections to 2050
  • Nested Bayesian meta-regression
  • Network meta-regression for alternative definitions
  • Projections to 2050

Main finding

As reported in the abstract

2020

Prevalent cases, global, 2020

619 million

95% UI 554–694

Age-standardised YLD rate, global, 2020

832 per 100 000

95% UI 578–1070

Further findings

Projected prevalent cases, global · 2050

Projected prevalent cases
843 million (UI 759-933)

Change in age-standardised rates, 1990–2020

Decrease in age-standardised prevalence rate (10.9-10.0)
10.4%
Decrease in age-standardised YLD rate (11.1-10.0)
10.5%

Years lived with disability (YLDs) attributable to occupational factors, smoking and high BMI

Proportion of YLDs attributable (28.7-47.0)
38.8%

Original publication

Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol. Published 22 May 2023. doi:10.1016/s2665-9913(23)00098-x

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