Global burden of early-onset osteoarthritis, 1990–2019: results from the Global Burden of Disease Study 2019
Authors' conclusion
Early-onset OA is a developing global health problem, causing substantial economic costs in most countries.
Study context
- Population
- Early-onset osteoarthritis (OA) (diagnosis before age 55; symptomatic and radiographically confirmed OA in any joint), global, 1990 to 2019
- Primary endpoint
- Incident cases, prevalent cases, YLDs and corresponding age-standardised rates of early-onset OA
- Follow-up
- 1990 to 2019
Methodological detailspopulation-level burden estimates, average annual percentage changes of age-standardised rates
- Population-level burden estimates
- Average annual percentage changes of age-standardised rates
Primary result
As reported in the abstract
Burden of early-onset OA
- Global incident cases, prevalent cases and years lived with disability (YLDs) of early-onset OA, 1990 to 2019
- doubled
- Incident OA cases in 2019 under 55 years
- 52.31%
- Age-standardised rates of incidence, prevalence and YLDs increased globally and in all Sociodemographic Index (SDI) quintiles (fastest in low-middle SDI countries)
- all average annual percentage changes (AAPCs)>0, p<0.05
- Countries with increasing trends in all age-standardised rates
- 98.04%
Further findings
Economic burden of early-onset OA · 2019
- Healthcare expenditure
- US$46.17 billion
- Productivity loss cost
- US$60.70 billion
Attributable proportion of high body mass index (BMI) for early-onset OA, global · 1990 to 2019
- 1990
- 9.41%
- 2019
- 15.29%
Original publication
Global burden of early-onset osteoarthritis, 1990–2019: results from the Global Burden of Disease Study 2019. Ann Rheum Dis. Published 12 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →