Systemic sclerosis & Raynaud's
Gastrointestinal disorders in systemic sclerosis: cluster analysis and prognosis from a French prospective cohort
Authors' conclusion
GIT manifestations are frequent and severe in SSc. Smoking appears to be associated with severe disease. Anorectal manifestations may be associated with cardiac disease
Study context
- Population
- Systemic sclerosis (SSc) patients, French prospective cohort, December 2019 to September 2021
- Participants
- 90 patients
- Outcome
- Prevalence of GIT manifestations
Methodological detailsobservational, hierarchical cluster analysis
- Observational
- Hierarchical cluster analysis
Main finding
As reported in the abstract
Gastro-oesophageal manifestations
93.3%
Intestinal manifestations
67.8%
Anorectal manifestations
18.9%
Observational data: associations, not effects.
Further findings
Associations with gastrointestinal tract (GIT) manifestations
- Correlation between anorectal disorders and cardiac disease
- Correlation between gastro-oesophageal involvement and impaired pulmonary function tests
- Smoking significantly associated with occurrence of severe GIT disorders
- Malnutrition frequent and associated with more cardiac and pulmonary disease
Cluster analysis
- Three groups of patients identified, including one cluster with cardiac and digestive involvement
Original publication
Gastrointestinal disorders in systemic sclerosis: cluster analysis and prognosis from a French prospective cohort. Clin Exp Rheumatol. Published 14 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →