Vasculitis & polymyalgia rheumatica
Frailty and Associated Outcomes in Patients With Vasculitis
Authors' conclusion
Self-reported frailty or prefrailty is common in the majority of patients with multiple forms of vasculitis, indicating there is a substantial subset of patients at risk for worse outcomes.
Study context
- Population
- Patients with vasculitis in the Vasculitis Patient-Powered Research Network (VascStrong)272 answered follow-up
- Participants
- 328 patients
- Outcome
- Frequency of self-reported frailty (FRAIL scale) and associated outcomes
- Follow-up
- baseline and 1-year follow-up
Methodological detailslongitudinal, internet-based cohort, multivariable logistic regression
- Longitudinal
- Internet-based cohort
- Multivariable logistic regression
Main finding
As reported in the abstract
Prevalence of prefrailty and frailty · baseline
Observational data: associations, not effects.
Further findings
Patient-Reported Outcomes Measurement Information System (PROMIS) scores · baseline and follow-up
- Prefrail and frail patients reported worse PROMIS scores
Factors associated with frailty
- Frailty independently associated with female sex, higher patient global assessment (PtGA) scores, overweight and obesity, but not with age
Transitions in frailty status · 1 year
- Patients with transitions in frailty status
- 99 (36.4%)
Hospitalizations and flares · 1 year
- More frequent in frail patients
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Frailty and Associated Outcomes in Patients With Vasculitis. J Rheumatol. Published 15 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →