Sjögren's disease & overlap diseases

Field testing and clinical validation of the mSQUASH to measure physical activity in patients with Sjögren's disease

Clin Exp RheumatolPublished Validation study

Authors' conclusion

The mSQUASH is a feasible, valid and reliable questionnaire to assess daily physical activity in SjD patients.

Study context

Population
Patients with Sjögren's disease (SjD); field testing also in SLE, GCA/PMR and axSpA263 SjD for construct validity
Participants
10 / 10 / 10 / 13
Comparison
SjD vs SLE vs GCA/PMR vs axSpA
  • SjDn = 10
  • SLEn = 10
  • GCA/PMRn = 10
  • axSpAn = 13
Outcome
Construct validity and test-retest reliability of the mSQUASH in SjD
Methodological detailsfield testing with semi-structured interviews, construct validity (Spearman correlations), test-retest reliability (ICC, Bland-Altman)
  • Field testing with semi-structured interviews
  • Construct validity (Spearman correlations)
  • Test-retest reliability (ICC, Bland-Altman)

Performance

As reported in the abstract

Correlation of mSQUASH total score with ESSPRI total score (Spearman ρ)

−0.30

Correlation of mSQUASH total score with EQ-5D total score (Spearman ρ)

−0.34

Test-retest reliability, ICC (n=75 SjD)

0.84

Further findings

Field testing

All patient groups perceived the mSQUASH as relevant and easy to complete; some minor adaptations and clarifications implemented

Subdomain correlations

Correlations higher for ESSPRI fatigue and pain than dryness, and highest for EQ-5D activity and mobility

Original publication

Field testing and clinical validation of the mSQUASH to measure physical activity in patients with Sjögren's disease. Clin Exp Rheumatol. Published 3 September 2024. doi:10.55563/clinexprheumatol/lcbs9m

Composed by AI from the published abstract and checked against it. How Briefs are made →

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