Sjögren's disease & overlap diseases

Physical activity in patients with Sjögren’s disease: Compliance with World Health Organization recommendations and relationship with health-related quality of life

Semin Arthritis RheumPublished Cross-sectional study

Authors' conclusion

Almost all patients with SjD performed aerobic PA, but patients could integrate more muscle strengthening and functional balance activities according to the WHO PA recommendations. Higher levels of PA were significantly associated with better HR-QoL.

Study context

Population
Consecutive patients with Sjögren's disease (SjD) from the RESULT cohort
Participants
245 patients
Outcome
Types of PA, compliance with World Health Organization (WHO) PA recommendations (mSQUASH) and association of PA levels with health-related quality of life (HR-QoL) (SF-36 domains)
Methodological detailsconsecutive patients, linear regression
  • Consecutive patients
  • Linear regression

Main finding

As reported in the abstract

Compliance with WHO PA recommendation components
Fulfilled aerobic physical activity (PA) component (≥150 min)
92 %
Fulfilled muscle strengthening component (≥2 times/week)
31 %
Fulfilled functional balance component (≥3 times/week)
7 %
Association of mSQUASH scores with SF-36 physical functioning, R2
0.19
Association of mSQUASH scores with SF-36 role limitations due to physical health, R2
0.17

Observational data: associations, not effects.

Further findings

Types of PA reported

%

Household activities
91
Walking
88
Cycling
62
Sports and exercise (most often fitness, physiotherapy/sport, group lessons, swimming and yoga)
55

Original publication

Physical activity in patients with Sjögren’s disease: Compliance with World Health Organization recommendations and relationship with health-related quality of life. Semin Arthritis Rheum. Published 28 August 2025. doi:10.1016/j.semarthrit.2025.152820

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