Features of Knee and Multijoint Osteoarthritis by Sex and Race and Ethnicity: A Preliminary Analysis in the Johnston County Health Study
Authors' conclusion
Preliminary findings in the diverse JoCoHS cohort suggest more lower extremity- predominant MJOA in men compared to women. Women and Black participants had more KOA features and more severe symptoms. Hispanic participants appear to have higher pain and symptoms scores despite having fewer structural changes.
Study context
- Population
- Participants enrolled in the Johnston County Health Study (JoCoHS) as of January 2023
- Participants
- 544 participants
- Exposure
- Knee and multijoint OA features by sex and by race and ethnicity
- Outcome
- Radiographic and symptomatic knee OA (KOA) and multijoint OA (MJOA) phenotypes
Methodological detailspopulation-based cohort, preliminary analysis, adjusted for age, BMI and education
- Population-based cohort
- Preliminary analysis
- Adjusted for age, BMI and education
Main finding
As reported in the abstract
KOA and MJOA phenotypes and symptoms by sex and race and ethnicity
- Black vs White · more severe knee osteoarthritis (KOA)
- OR 1.47
- Black vs White · subchondral sclerosis
- OR 2.06
- Black vs White · medial tibial osteophytes
- OR 1.50
- Black vs White · worse KOOS Symptoms
- MR 1.18
- Women vs Men · significantly worse KOOS Symptoms
- MR 1.25
Observational data: associations, not effects.
Original publication
Features of Knee and Multijoint Osteoarthritis by Sex and Race and Ethnicity: A Preliminary Analysis in the Johnston County Health Study. J Rheumatol. Published 15 September 2023. doi:10.
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