Spondyloarthritis & psoriatic arthritis
Factors Associated With Residual Disease in Axial Spondyloarthritis: Results From a Clinical Practice Registry
Authors' conclusion
Residual disease is frequent in patients with axSpA who are in an LDA state, including remission, and it is particularly prevalent in female patients.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) in an low disease activity (LDA) state (Ankylosing Spondylitis Disease Activity Score (ASDAS) < 2.1) from SpA-Net, a web-based monitoring registry for SpAmean age 50.6 years
- Participants
- 267 patients
- Exposure
- Female vs male patients
- Femalen = 100
- Outcome
- Fatigue (indicator of residual disease)
Methodological detailsregistry-based (SpA-Net), logistic and linear regression, multivariable
- Registry-based (SpA-Net)
- Logistic and linear regression
- Multivariable
Main finding
As reported in the abstract
Fatigue
Each group vs maleOdds ratio (fatigue > 4/10) (95% CI)
Female
3.29(1.74–6.20)
- Female
- B (fatigue severity 0-10) 0.78 (95% CI 0.18–1.38)
- Fatigue scores > 4/10, all patients
- 114 [42.7%]
Observational data: associations, not effects.
Further findings
Pain scores > 4/10, all patients
- Pain scores > 4/10
- 34 [17.8%]
Physical health-related quality of life (HRQOL), all patients
- Physical HRQOL reduced
- 27%
- Physical HRQOL moderate/poor
- 33%
Other indicators of residual disease (pain, peripheral symptoms, physical HRQOL) by sex
- More severe and/or more prevalent in females
Original publication
Factors Associated With Residual Disease in Axial Spondyloarthritis: Results From a Clinical Practice Registry. J Rheumatol. Published 15 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →