Spondyloarthritis & psoriatic arthritis
Extent of axial damage in psoriatic arthritis and spondyloarthritis: comparative data from the BEPAS and (Be-)GIANT multicentre cohorts
Authors' conclusion
Minimal radiographic spinal damage was observed in Belgian patients with PsA or SpA. Patients with SpA tend to have higher mSASSS values and more syndesmophytes compared with PsA. Syndesmophytes were more often located in the cervical spine of patients with PsA, while the location was equally distributed in axSpA.
Study context
- Population
- Patients with PsA and spondyloarthritis (SpA) in private and academic Belgian practices
- Participants
- 525 patients
- Exposure
- PsA vs SpA
- PsAn = 312
- SpAn = 213reference
- Outcome
- Radiographic axial damage: mSASSS (spine) and modified New York criteria (pelvis) on baseline radiographs
- Follow-up
- Baseline
Methodological detailsmulticentre cohorts, blinded readers, two calibrated readers
- Multicentre cohorts
- Blinded readers
- Two calibrated readers
Main finding
As reported in the abstract
Normal spinal radiographs
Observational data: associations, not effects.
Further findings
Syndesmophyte location, cervical spine · baseline
Syndesmophyte location, lumbar spine · baseline
- Modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) in patients with spinal damage · baseline · higher mSASSS in SpA
- P < 0.05
- Syndesmophyte location, cervical spine: denominators: PsA 33, SpA 14
- Syndesmophyte location, lumbar spine: denominators: PsA 33, SpA 14
Original publication
Extent of axial damage in psoriatic arthritis and spondyloarthritis: comparative data from the BEPAS and (Be-)GIANT multicentre cohorts. RMD Open. Published 3 May 2023. doi:10.
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