Spondyloarthritis & psoriatic arthritis
Coexistence of sarcoidosis and spondyloarthritis: a rare but intriguing association
Authors' conclusion
We have characterised 23 patients who fulfilled the current classification criteria for both SpA and sarcoidosis. Therefore, sarcoidosis may coexist with SpA like other systemic autoimmune diseases, and this may be explained by shared pathogenic mechanisms.
Study context
- Population
- Patients fulfilling ASAS criteria for SpA and WASOG criteria for sarcoidosis, two large multicentre registries14 females and 9 males
- Participants
- 23 patients
- Exposure
- Sarcoidosis after SpA vs Sarcoidosis preceded SpA vs Concurrent
- Sarcoidosis after SpAn = 8
- Sarcoidosis preceded SpAn = 9
- Concurrentn = 6
- Outcome
- Timing of diagnoses and HLA-B27 in patients with coexisting sarcoidosis and SpA
Methodological detailsmulticentre, two registries (Sjögren Syndrome Big Data Consortium and Sarco-GEAS-SEMI Registry)
- Multicentre
- Two registries (Sjögren Syndrome Big Data Consortium and Sarco-GEAS-SEMI Registry)
Main finding
As reported in the abstract
Sarcoidosis after SpA
8
events
Sarcoidosis preceded SpA
9
events
Concurrent
6
events
Observational data: associations, not effects.
Original publication
Coexistence of sarcoidosis and spondyloarthritis: a rare but intriguing association. Clin Exp Rheumatol. Published 18 September 2025. doi:10.
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