Exploring the association of gender role expectations of pain and measures of pain sensitization in people with knee osteoarthritis: A cross-sectional study
Authors' conclusion
This first exploration of gendered pain sensitivity and pain endurance by males and females has small and clinically unimportant associations with measures of pain sensitization requiring further validation.
Study context
- Population
- People aged ≥40, English or French speaking, with knee osteoarthritis (OA) (ACR criteria) consulting an orthopedic surgeon57% females
- Participants
- 280 people
- Outcome
- Association between GREP scores and psychophysical measures of sensitization (pressure pain thresholds (PPTs), Temporal Summation (TS), CPM)
Methodological detailssecondary analyses of a cohort study, multiple linear regression, adjusted for age, BMI, pain catastrophizing, anxio-depressive symptoms and radiographic severity, stratified on median split of Gender Role Expectations of Pain (GREP) scores
- Secondary analyses of a cohort study
- Multiple linear regression
- Adjusted for age, BMI, pain catastrophizing, anxio-depressive symptoms and radiographic severity
- Stratified on median split of GREP scores
Main finding
As reported in the abstract
Association of GREP pain sensitivity scores with CPM values in males
GREP pain sensitivity scores in males vs Conditioned Pain Modulation (CPM) values, β
0.09 (0.01 to 0.17) (95% CI)
Observational data: associations, not effects.
Further findings
Males with low GREP pain sensitivity or pain endurance (stratified)
- Very small to small positive associations with PPT and CPM values
Original publication
Exploring the association of gender role expectations of pain and measures of pain sensitization in people with knee osteoarthritis: A cross-sectional study. Osteoarthritis Cartilage. Published 2 April 2024. doi:10.
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