Exploring physical activity patterns in adolescents with hypermobility spectrum disorder or hypermobile Ehlers-Danlos Syndrome
Authors' conclusion
According to this study, adolescents with HSD/hEDS exhibited physical activity behaviors at levels that are associated to poorer health compared to healthy peers.
Study context
- Population
- Adolescents aged 13–17 years with Hypermobility Spectrum Disorder (HSD)/Hypermobile Ehlers-Danlos Syndrome (hEDS) and healthy adolescents
- Participants
- 37 vs 45
- Exposure
- Adolescents with HSD/hEDS vs healthy adolescents
- HSD/hEDSn = 37
- Controln = 45reference
- Outcome
- Physical activity patterns (daytime and nighttime movement behavior) measured with accelerometers
Methodological detailsaccelerometer-measured physical activity, healthy control group
- Accelerometer-measured physical activity
- Healthy control group
Main finding
As reported in the abstract
Physical activity patterns (accelerometer)
- HSD/hEDS spent significantly more time in sedentary behavior (SED) vs control
- HSD/hEDS spent less time in moderate-to-vigorous physical activity (MVPA) vs control
- HSD/hEDS exhibited significantly more sleep movement during night vs control
Observational data: associations, not effects.
Further findings
Association between fatigue and SED, MVPA daytime or sleep movement in HSD/hEDS (pain catastrophizing as confounder)
- Association could not be confirmed
Original publication
Exploring physical activity patterns in adolescents with hypermobility spectrum disorder or hypermobile Ehlers-Danlos Syndrome. Pediatr Rheumatol Online J. Published 8 July 2025. doi:10.
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