Vasculitis & polymyalgia rheumatica
Examination of nailfold videocapillaroscopy findings in ANCA-associated vasculitis
Authors' conclusion
In AAV patients, NVC abnormalities are significantly associated with disease severity.
Study context
- Population
- Patients with AAV and healthy controls
- Participants
- 51 vs 21
- Exposure
- AAV vs healthy controls
- AAVn = 51
- Healthy controlsn = 21reference
- Outcome
- NVC findings (semiquantitative scores) and their association with disease activity
Methodological detailscase-control comparison with healthy controls, 3-month follow-up after immunosuppressive therapy
- Case-control comparison with healthy controls
- 3-month follow-up after immunosuppressive therapy
Main finding
As reported in the abstract
| Group | Value | Microangiopathy pattern | Scleroderma pattern |
|---|---|---|---|
| AAV | 70.6% | 36 (70.6%) | 4 (7.8%) |
AAV
Value70.6%
Microangiopathy pattern36 (70.6%)
Scleroderma pattern4 (7.8%)
Observational data: associations, not effects.
Further findings
- Microhaemorrhage scores significantly reduced after 3 months of immunosuppressive therapy
Original publication
Examination of nailfold videocapillaroscopy findings in ANCA-associated vasculitis. Rheumatology (Oxford). Published 11 July 2022. doi:10. 1093/ rheumatology/ keac402
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