Vasculitis & polymyalgia rheumatica

Examination of nailfold videocapillaroscopy findings in ANCA-associated vasculitis

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

In AAV patients, NVC abnormalities are significantly associated with disease severity.

Study context

Population
Patients with AAV and healthy controls
Participants
51 vs 21
Exposure
AAV vs healthy controls
  • AAVn = 51
  • Healthy controlsn = 21reference
Outcome
NVC findings (semiquantitative scores) and their association with disease activity
Methodological detailscase-control comparison with healthy controls, 3-month follow-up after immunosuppressive therapy
  • Case-control comparison with healthy controls
  • 3-month follow-up after immunosuppressive therapy

Main finding

As reported in the abstract

GroupValueMicroangiopathy patternScleroderma pattern
AAV70.6%36 (70.6%)4 (7.8%)

AAV

Value70.6%
Microangiopathy pattern36 (70.6%)
Scleroderma pattern4 (7.8%)

Observational data: associations, not effects.

Further findings

Microhaemorrhage scores significantly reduced after 3 months of immunosuppressive therapy

Original publication

Examination of nailfold videocapillaroscopy findings in ANCA-associated vasculitis. Rheumatology (Oxford). Published 11 July 2022. doi:10.1093/rheumatology/keac402

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