Vasculitis & polymyalgia rheumatica
Evaluation of common femoral vein thickness as a diagnostic tool for Behçet's disease in a non-endemic area
Authors' conclusion
In this study, CFVT measurement was not shown to be a reliable diagnostic test for BD. CFVT was increased in BD patients presenting vascular involvement and correlated with the number of previous events.
Study context
- Population
- Brazilian patients with Behçet's disease (BD) (non-endemic area) and controls
- Participants
- 100 vs 100
- Exposure
- BD patients vs controls
- BDn = 100
- Controlsn = 100reference
- Outcome
- CFVT measured by Doppler US as a diagnostic tool for BD
Methodological detailsdiagnostic evaluation by Doppler US
- Diagnostic evaluation by Doppler US
Main finding
As reported in the abstract
Right CFVT, median (range as printed)
| Group | Value | AUC (right common femoral vein thickness (CFVT), 0.575mm cut-off) | Sensitivity (right CFVT) | Specificity (right CFVT) | AUC (left CFVT, 0.575mm cut-off) | Sensitivity (left CFVT) | Specificity (left CFVT) |
|---|---|---|---|---|---|---|---|
| BD | 0.600 (interval 0.500–0.700) mm | 0.602 | 52% | 64% | 0.615 | 43% | 77% |
| Controls | 0.525 (interval 0.450–0.637) mm |
Value
BD0.600 (interval 0.500–0.700) mm
Controls0.525 (interval 0.450–0.637) mm
AUC (right common femoral vein thickness (CFVT), 0.575mm cut-off)
BD0.602
Controls— not stated in the abstract
Sensitivity (right CFVT)
BD52%
Controls— not stated in the abstract
Specificity (right CFVT)
BD64%
Controls— not stated in the abstract
AUC (left CFVT, 0.575mm cut-off)
BD0.615
Controls— not stated in the abstract
Sensitivity (left CFVT)
BD43%
Controls— not stated in the abstract
Specificity (left CFVT)
BD77%
Controls— not stated in the abstract
- BD vs Controls: P = 0.012 — right CFVT higher in BD
Observational data: associations, not effects.
Further findings
Left CFVT · left CFVT higher in BD
P = 0.004
Association of vascular involvement and previous DVT with increased CFVT
- Vascular involvement of BD and previous DVT associated with increased CFVT
- P < 0.05
Correlation of number of vascular events with CFVT
- Right CFVT, Rho = 0.475
- P = 0.030
- Left CFVT, Rho = 0.429
- P = 0.052
Great saphenous vein (GSV) and small saphenous vein (SSV) diameters in both legs
- No significant differences between BD and controls
- P > 0.05
Original publication
Evaluation of common femoral vein thickness as a diagnostic tool for Behçet's disease in a non-endemic area. Clin Exp Rheumatol. Published 23 November 2023. doi:10.
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