Spondyloarthritis & psoriatic arthritis
Equivalent cut-off values of Bath Ankylosing Spondylitis Disease Activity Index corresponding to Ankylosing Spondylitis Disease Activity Score cut-off values
Authors' conclusion
The BASDAI values 1.6, 2.9 and 3.8 correspond to ASDAS-CRP values 1.3, 2.1 and 3.5, respectively. The ΔBASDAI 1.6 and 2.0 best correspond to the ΔASDAS-CRP 1.1 and 2.0, respectively.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) with Bath ankylosing Spondylitis Disease Activity Index (BASDAI) and Ankylosing Spondylitis Disease Activity Score (ASDAS) data available154 with ΔBASDAI and ΔASDAS-CRP data
- Participants
- 475 patients
- Comparison
- BASDAI cut-off values vs ASDAS-CRP cut-off values
- Outcome
- BASDAI cut-off values best corresponding to ASDAS-CRP cut-off values
Methodological detailsROC analysis, Cohen's kappa agreement
- ROC analysis
- Cohen's kappa agreement
Performance
As reported in the abstract
BASDAI values best corresponding to ASDAS-CRP cut-offs (ROC)
BASDAI 1.6 corresponds to ASDAS-CRP 1.3 (AUC)
0.948
BASDAI 2.9 corresponds to ASDAS-CRP 2.1 (AUC)
0.790
BASDAI 3.8 corresponds to ASDAS-CRP 3.5 (AUC)
0.875
Agreement between disease activity states, moderate (kappa)
0.527
Further findings
Disease activity by ASDAS-CRP
- Inactive
- 88 (18.6%)
- Moderate
- 130 (27.4%)
- High
- 191 (40.1%)
- Very high
- 66 (13.9%)
ΔBASDAI corresponding to ΔASDAS-CRP improvement thresholds (ROC)
- ΔBASDAI 1.6 corresponds to ΔASDAS-CRP 1.1 (minimal clinically important improvement) (AUC)
- 0.745
- ΔBASDAI 2.0 corresponds to ΔASDAS-CRP 2.0 (major improvement) (AUC)
- 0.708
- Agreement, good (kappa)
- 0.685
Original publication
Equivalent cut-off values of Bath Ankylosing Spondylitis Disease Activity Index corresponding to Ankylosing Spondylitis Disease Activity Score cut-off values. Clin Exp Rheumatol. Published 29 June 2022. doi:10.
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